Allosteric is an English word. Below you'll find 10+ example sentences showing how it's used in practice.
Allosteric meaning
That binds a compound on an inactive site and thus changes macromolecular conformation or dynamics in order to become either active or inactive
Using Allosteric
- The main meaning on this page is: That binds a compound on an inactive site and thus changes macromolecular conformation or dynamics in order to become either active or inactive
- In the example corpus, allosteric often appears in combinations such as: an allosteric, allosteric effector, the allosteric.
Context around Allosteric
- Average sentence length in these examples: 26.7 words
- Position in the sentence: 3 start, 5 middle, 5 end
- Sentence types: 13 statements, 0 questions, 0 exclamations
Corpus analysis for Allosteric
- In this selection, "allosteric" usually appears in the middle of the sentence. The average example has 26.7 words, and this corpus slice is mostly made up of statements.
- Around the word, known, specific, protein, effector, effect and mechanism stand out and add context to how "allosteric" is used.
- Recognizable usage signals include a heterotropic allosteric effect and and negative allosteric modulatory actions. That gives this page its own corpus information beyond isolated example sentences.
- By corpus frequency, "allosteric" sits close to words such as aaronson, abai and abass, which helps place it inside the broader word index.
Example types with allosteric
The same corpus examples are grouped by length and sentence type, making it easier to see the contexts in which the word appears:
This triggers an allosteric response mediated by the linker region (labeled). (11 words)
ATP competes with AMP for the allosteric effector site on the PFK enzyme. (13 words)
These functions are, in part, controlled by allosteric modification by secondary messengers and reversible protein phosphorylation. (16 words)
Iron's shift to a higher oxidation state in Hb-O 2 decreases the atom's size, and allows it into the plane of the porphyrin ring, pulling on the coordinated histidine residue and initiating the allosteric changes seen in the globulins. (42 words)
These molecules then cause a change in the conformation or dynamics of the enzyme that is transduced to the active site and thus affects the reaction rate of the enzyme. citation In this way, allosteric interactions can either inhibit or activate enzymes. (42 words)
This type of regulation often involves allosteric regulation of the activities of multiple enzymes in the pathway. citation Extrinsic control involves a cell in a multicellular organism changing its metabolism in response to signals from other cells. (37 words)
Example sentences (13)
There is no known allosteric mechanism that can account for large changes in reaction rate from an allosteric effector whose concentration changes less than 10%. citation Calcium is used as a regulator.
We are currently working on highly differentiated and novel chemical series identified from our proprietary chemical library of small molecules with our specific allosteric modulation biological assays.
Unlike core protein allosteric modulators, ZM-H1505R is a novel pyrazole molecule with a new binding site in the HBV core protein that inhibits HBV replication.
ATP competes with AMP for the allosteric effector site on the PFK enzyme.
In some cases, the inhibitor can bind to a site other than the binding-site of the usual substrate and exert an allosteric effect to change the shape of the usual binding-site.
Iron's shift to a higher oxidation state in Hb-O 2 decreases the atom's size, and allows it into the plane of the porphyrin ring, pulling on the coordinated histidine residue and initiating the allosteric changes seen in the globulins.
One recognition site acts as the target for cleavage, while the other acts as an allosteric effector that speeds up or improves the efficiency of enzyme cleavage.
These functions are, in part, controlled by allosteric modification by secondary messengers and reversible protein phosphorylation.
These molecules then cause a change in the conformation or dynamics of the enzyme that is transduced to the active site and thus affects the reaction rate of the enzyme. citation In this way, allosteric interactions can either inhibit or activate enzymes.
This is because ethanol's effects on these channels are a summation of positive and negative allosteric modulatory actions.
This phenomenon, where molecule Y affects the binding of molecule X to a transport molecule Z, is called a heterotropic allosteric effect.
This triggers an allosteric response mediated by the linker region (labeled).
This type of regulation often involves allosteric regulation of the activities of multiple enzymes in the pathway. citation Extrinsic control involves a cell in a multicellular organism changing its metabolism in response to signals from other cells.
Common combinations with allosteric
These word pairs occur most frequently in English texts:
- an allosteric 5×
- allosteric effector 3×
- the allosteric 2×
- allosteric effect 2×