Wondering how to use Antisense in a sentence? Below are 10+ example sentences from authentic English texts. Including the meaning .
Antisense in a sentence
Antisense meaning
The strand of nucleic acid complementary to a strand which codes for an RNA or protein.
Using Antisense
- The main meaning on this page is: The strand of nucleic acid complementary to a strand which codes for an RNA or protein.
- In the example corpus, antisense often appears in combinations such as: antisense oligonucleotides, and antisense, antisense drug.
Context around Antisense
- Average sentence length in these examples: 24.5 words
- Position in the sentence: 4 start, 7 middle, 4 end
- Sentence types: 15 statements, 0 questions, 0 exclamations
Corpus analysis for Antisense
- In this selection, "antisense" usually appears in the middle of the sentence. The average example has 24.5 words, and this corpus slice is mostly made up of statements.
- Around the word, morpholino, using, preclinical, oligonucleotides, drug and technology stand out and add context to how "antisense" is used.
- Recognizable usage signals include a gene antisense to xist and an antisense structural type. That gives this page its own corpus information beyond isolated example sentences.
- By corpus frequency, "antisense" sits close to words such as aaaa, abductees and abdulahi, which helps place it inside the broader word index.
Example types with antisense
The same corpus examples are grouped by length and sentence type, making it easier to see the contexts in which the word appears:
He will be responsible for leading preclinical antisense drug discovery and antisense technology research. (14 words)
An antisense structural type that has proven especially valuable in research is morpholino antisense. (14 words)
A common reverse genetics technique is to reduce gene expression or modify splicing using Morpholino antisense technology. (17 words)
This therapy also represents the beginning of cancer immunogene therapy, a treatment which proves to be effective due to the anti-tumor mechanism of IGF-I antisense, which is related to strong immune and apoptotic phenomena. (36 words)
Using these insights, the researchers devised a way to set off a signal to open the barrier in a mouse model for enough time to deliver drugs called antisense oligonucleotides, to the peripheral nervous system. (35 words)
This approach can be implemented to design self-assembled triplex structures from any other miR combination, or from other genetic materials including antisense DNA or siRNA to treat a range of diseases. (32 words)
Example sentences (15)
He will be responsible for leading preclinical antisense drug discovery and antisense technology research.
An antisense structural type that has proven especially valuable in research is morpholino antisense.
Both sense and antisense sequences can exist on different parts of the same strand of DNA (i.e. both strands can contain both sense and antisense sequences).
Using these insights, the researchers devised a way to set off a signal to open the barrier in a mouse model for enough time to deliver drugs called antisense oligonucleotides, to the peripheral nervous system.
In a promising development, the team developed an intervention strategy using antisense oligonucleotides (ASO) to reduce IgG content in mouse tissues, thereby delaying the aging of multiple organs.
Stoke Therapeutics, Inc, an early-stage biopharmaceutical company, develops antisense oligonucleotide medicines to treat the underlying causes of severe genetic diseases.
This antisense drug is currently being evaluated in a mid-stage study, with data expected in the first half of 2020.
A common reverse genetics technique is to reduce gene expression or modify splicing using Morpholino antisense technology.
Gene expression knockdown techniques The expression of genes can be reduced by a variety of means, for example by using antisense oligonucleotides targeting specific mRNA molecules.
Lee, J. T., Davidow, L. S., Warshawsky, D., (1999), Tisx, a gene antisense to Xist at the X-inactivation centre.
Like all antisense approaches, different MOs can have different efficacy, and may cause off-target, non-specific effects.
Promoters are located near the transcription start sites of genes, on the same strand and upstream on the DNA (towards the 5' region of the antisense strand ).
Scientists from Karolinska Institutet and the University of Oxford use electroporation of exosomes to deliver siRNAs, antisense oligonucleotides, chemotherapeutic agents and proteins specifically to neurons after inject them systemically (in blood).
This approach can be implemented to design self-assembled triplex structures from any other miR combination, or from other genetic materials including antisense DNA or siRNA to treat a range of diseases.
This therapy also represents the beginning of cancer immunogene therapy, a treatment which proves to be effective due to the anti-tumor mechanism of IGF-I antisense, which is related to strong immune and apoptotic phenomena.
Common combinations with antisense
These word pairs occur most frequently in English texts: