Wondering how to use Clozapine in a sentence? Below are 10+ example sentences from authentic English texts. Including the meaning and synonyms such as antipsychotic or neuroleptic.
Clozapine in a sentence
Clozapine meaning
A sedative drug used to treat schizophrenia.
Synonyms of Clozapine
Using Clozapine
- The main meaning on this page is: A sedative drug used to treat schizophrenia.
- Useful related words include: clozaril, neuroleptic agent, neuroleptic drug, antipsychotic.
- In the example corpus, clozapine often appears in combinations such as: clozapine is, of clozapine, except clozapine.
Context around Clozapine
- Average sentence length in these examples: 18.2 words
- Position in the sentence: 4 start, 6 middle, 3 end
- Sentence types: 13 statements, 0 questions, 0 exclamations
Corpus analysis for Clozapine
- In this selection, "clozapine" usually appears in the middle of the sentence. The average example has 18.2 words, and this corpus slice is mostly made up of statements.
- Around the word, except, assess, history, act and may stand out and add context to how "clozapine" is used.
- Recognizable usage signals include antipsychotics except clozapine act on and chlorpromazine and clozapine are antagonists. That gives this page its own corpus information beyond isolated example sentences.
- By corpus frequency, "clozapine" sits close to words such as aami, abada and abbottabad, which helps place it inside the broader word index.
Example types with clozapine
The same corpus examples are grouped by length and sentence type, making it easier to see the contexts in which the word appears:
Side effects Clozapine may cause side effects. (7 words)
All of the effective antipsychotics, except clozapine, act on the nigrostriatal system. (12 words)
Clozapine was discovered in the 1960s and began being used in healthcare in 1971. (14 words)
The risk of developing extrapyramidal symptoms such as tardive dyskinesia is below that of typical antipsychotics ; this may be due to clozapine's anticholinergic effects. (25 words)
For example, drugs used to treat patients with schizophrenia such as haloperidol, chlorpromazine, and clozapine are antagonists at receptors in the brain for dopamine. (24 words)
History Clozapine was developed by Sandoz in 1961, and trials took place in 1972, when it was released in Switzerland and Austria as Leponex. (24 words)
Example sentences (13)
Although our results were underpowered to assess clozapine, we did note a rate reduction using the suspicions register.
All of the effective antipsychotics, except clozapine, act on the nigrostriatal system.
Antipsychotics All antipsychotic substances, except clozapine, are relatively potent postsynaptic dopamine receptor blockers (dopamine antagonists ).
Clozapine is associated with a relatively high risk of low white blood cells which may result in death.
Clozapine is extensively metabolized in the liver, via the cytochrome P450 system, to polar metabolites suitable for elimination in the urine and feces.
Clozapine was discovered in the 1960s and began being used in healthcare in 1971.
For example, drugs used to treat patients with schizophrenia such as haloperidol, chlorpromazine, and clozapine are antagonists at receptors in the brain for dopamine.
History Clozapine was developed by Sandoz in 1961, and trials took place in 1972, when it was released in Switzerland and Austria as Leponex.
If carbamazepine is discontinued or the dose of carbamazepine is decreased, therapeutic effects of clozapine should be monitored.
It has been recommended that patients, families, and caregivers are aware of the symptoms and risks of abrupt withdrawal of clozapine.
Side effects Clozapine may cause side effects.
The elimination half-life of clozapine is about 14 hours at steady state conditions (varying with daily dose).
The risk of developing extrapyramidal symptoms such as tardive dyskinesia is below that of typical antipsychotics ; this may be due to clozapine's anticholinergic effects.
Common combinations with clozapine
These word pairs occur most frequently in English texts:
- clozapine is 3×
- of clozapine 3×
- except clozapine 2×
- clozapine are 2×
- clozapine was 2×