Get to know Cyclin better with 9 real example sentences, the meaning.
Cyclin meaning
Any of a group of proteins whose presence in a cell varies through its cycle, and that regulates this cycle by forming a complex with kinase
Using Cyclin
- The main meaning on this page is: Any of a group of proteins whose presence in a cell varies through its cycle, and that regulates this cycle by forming a complex with kinase
- In the example corpus, cyclin often appears in combinations such as: cyclin d-cdk.
Context around Cyclin
- Average sentence length in these examples: 23.4 words
- Position in the sentence: 5 start, 3 middle, 1 end
- Sentence types: 9 statements, 0 questions, 0 exclamations
Corpus analysis for Cyclin
- In this selection, "cyclin" usually appears near the start of the sentence. The average example has 23.4 words, and this corpus slice is mostly made up of statements.
- Around the word, cdk, associated, particular, cdk, dependent and complex stand out and add context to how "cyclin" is used.
- Recognizable usage signals include a bound cyclin cdks perform and a cdk cyclin complex has. That gives this page its own corpus information beyond isolated example sentences.
- By corpus frequency, "cyclin" sits close to words such as aab, aamer and aave, which helps place it inside the broader word index.
Example types with cyclin
The same corpus examples are grouped by length and sentence type, making it easier to see the contexts in which the word appears:
Different cyclin-CDK combinations determine the downstream proteins targeted. (9 words)
Cyclin D-CDK4 complex in turn phosphorylates the retinoblastoma susceptibility protein ( Rb ). (12 words)
G1 cyclin-CDK activities are not the driver of cell cycle entry. (12 words)
However, results from a recent study of E2F transcriptional dynamics at the single-cell level argue that the role of G1 cyclin-CDK activities, in particular cyclin D-CDK4/6, is to tune the timing rather than the commitment of cell cycle entry. (43 words)
An example of this in cell biology is that activated CDK1 (Cyclin Dependent Kinase 1) activates its activator Cdc25 while at the same time inactivating its inactivator, Wee1, thus allowing for progression of a cell into mitosis. (37 words)
When activated by a bound cyclin, CDKs perform a common biochemical reaction called phosphorylation that activates or inactivates target proteins to orchestrate coordinated entry into the next phase of the cell cycle. (32 words)
Example sentences (9)
After a CDK-cyclin complex has performed its function, the associated cyclin is polyubiquitinated and destroyed by the proteasome, which provides directionality for the cell cycle.
However, results from a recent study of E2F transcriptional dynamics at the single-cell level argue that the role of G1 cyclin-CDK activities, in particular cyclin D-CDK4/6, is to tune the timing rather than the commitment of cell cycle entry.
Cdk5 is a divergent member of the cyclin-dependent kinase family, Cdk5α is a essential activating subunit which is uniquely expressed in postmitotic neurons.
An example of this in cell biology is that activated CDK1 (Cyclin Dependent Kinase 1) activates its activator Cdc25 while at the same time inactivating its inactivator, Wee1, thus allowing for progression of a cell into mitosis.
Cyclin D-CDK4 complex in turn phosphorylates the retinoblastoma susceptibility protein ( Rb ).
Different cyclin-CDK combinations determine the downstream proteins targeted.
G1 cyclin-CDK activities are not the driver of cell cycle entry.
They halt cell cycle in G 1 phase, by binding to, and inactivating, cyclin-CDK complexes.
When activated by a bound cyclin, CDKs perform a common biochemical reaction called phosphorylation that activates or inactivates target proteins to orchestrate coordinated entry into the next phase of the cell cycle.
Common combinations with cyclin
These word pairs occur most frequently in English texts:
- cyclin d-cdk 2×