Cytosol in a sentence

Cytosol main The cytosol is the portion of the cytoplasm not contained within membrane-bound organelles.

For example, when the pH in the cells environment drops, the H + ions surging into the cytosol can be transferred to a vacuole in order to keep the cytosol's pH constant. citation In animals, vacuoles serve in exocytosis and endocytosis processes.

The cell is additionally protected from any lysosomal acid hydrolases that drain into the cytosol, as these enzymes are pH-sensitive and do not function well or at all in the alkaline environment of the cytosol.

Adhesin uses a dedicated secretion pathway, with several steps occurring in the cytosol before its translocation across the membrane.

Acids that lose a proton at the intracellular pH will exist in their soluble, charged form and are thus able to diffuse through the cytosol to their target.

Also, ubiquitination appears to be crucial for the export of PEX5 from the peroxisome, to the cytosol.

Although water forms the large majority of the cytosol, its structure and properties within cells is not well understood.

Because egg cytosol can support successive cycling between mitosis and interphase in vitro, it has been critical to diverse studies of cell division.

Cells can deal with even larger osmotic changes by accumulating osmoprotectants such as betaines or trehalose in their cytosol.

Cytosol makes up about 70% of the cell volume and is a complex mixture of cytoskeleton filaments, dissolved molecules, and water.

During gluconeogenesis mitochondrial oxaloacetate is reduced to malate which is then transported out of the mitochondrion, to be oxidized back to oxaloacetate in the cytosol.

Glycolysis occurs in most organisms in the cytosol of the cell.

However, it is doubtful that this is a meaningful effect in vivo, because citrate in the cytosol is utilized mainly for conversion to acetyl-CoA for fatty acid and cholesterol synthesis.

However, this acetyl CoA needs to be transported into cytosol where the synthesis of fatty acids and cholesterol occurs.

Importantly, the transport of lipids through the cytosol and lipid flow through a continuous endomembrane system are not mutually exclusive processes and both may occur in cells.

It is oriented with the N-terminus outside the cell and the C-terminus in the cytosol.

Normally, mild calcium influx from cytosol into the mitochondrial matrix causes transient depolarization that is corrected by pumping out protons.

Once secretory proteins are formed, the ER membrane separates them from the proteins that will remain in the cytosol.

Protein compartments Some protein complexes contain a large central cavity that is isolated from the remainder of the cytosol.

Proteins that are formed from free ribosomes are released into the cytosol and used within the cell.