Igf in a sentence

The IGF-2 receptor only binds IGF-2 and acts as a "clearance receptor"—it activates no intracellular signaling pathways, functioning only as an IGF-2 sequestering agent and preventing IGF-2 signaling.

IGF receptors cause cancer cells to divide, and one study noted that the IGF receptor is found on breast cancer cells than healthy breast tissue.

Insulin-like growth factor 2 (IGF-2) is thought to be a primary growth factor required for early development while IGF-1 expression is required for achieving maximal growth.

The IGF-1 receptor is the "physiological" receptor— IGF-I binds to it at significantly higher affinity than it binds the insulin receptor.

Experts suspect the reduced lifespan in larger dog breeds is due in part to elevated levels of the growth-promoting hormone IGF-1, caused by selective breeding.

Those mice implanted with muscle tissue constructs that offered sustained release of IGF-1 exhibited the highest degree of muscle tissue regeneration six weeks after implantation.

Dr Ahlemann revealed that sugar consumption can cause levels of a hormone called insulin-like growth factor 1, or IGF-1, to rise.

Researchers also note that intake of dairy and other animal proteins has previously been associated with higher blood levels of the growth factor-1 (IGF-1) hormone, which is thought to promote certain cancers.

By artificially increasing milk output, rBGH also raises the levels of pus, antibiotic residues, and a cancer-accelerating hormone called IGF-1.

He further noted that other IGF sources included conveyance fee, tolls, business operation fee adding however that as a District, the Assembly’s charges was lower than that of a municipality or metropolis.

If you knock out IGF-1 and give growth hormone, it has no effect.

Mr Adomey said they would work closely with the Government on two main programmes: To revive the annual Ghana Internet Governance Forum (IGF) and to reduce or eradicate the syndrome of “fa ma nyame” in Ghana with regards to cyber security issues.

Mr. Kwame Adu Gyamfi, the Presiding Member of the Nkoranza Municipal Assembly, admitted the situation was seriously affecting the Assembly’s IGF mobilization.

Insulin-like growth factor 1 (IGF-1) is mainly secreted by the liver as a result of stimulation by growth hormone (GH).

Like the insulin receptor, the IGF-I receptor is a receptor tyrosine kinase —meaning the receptor signals by causing the addition of a phosphate molecule on particular tyrosines.

Receptors for IGF-I are found in vascular smooth muscle, while typical receptors for insulin are not found in vascular smooth muscle.

Researchers are not in complete agreement about the degree of cancer risk that IGF-1 poses.

The IGF axis has been shown to play roles in the promotion of cell proliferation and the inhibition of cell death ( apoptosis ).

The IGF opened an ongoing, non-binding conversation among stakeholders representing governments, the private sector, civil society, and the technical and academic communities about the future of Internet governance.

Therefore, it is an open question as to whether either IGF-1 or insulin in the mammal may perturb aging, although there is the suggestion that dietary restriction phenomena may be related.