Inhibitor in a sentence

Kura’s pipeline also includes KO-947, an ERK inhibitor, currently in a Phase 1 dose-escalation trial, and KO-539, a menin-MLL inhibitor, currently in IND-enabling studies.

It inhibits PDE4 to the greatest extent, but also shows significant inhibition of other PDE subtypes, and so acts as a selective PDE4 inhibitor or a non-selective phosphodiesterase inhibitor, depending on the dose.

Overall, they said those taking proton pump inhibitor acid reflux drugs for more than 4.4 years had 33% increased risk of developing dementia compared to those who didn’t take the drugs.

Similarly, featured another clone retcon in the form of Order 66 and the inhibitor chips, with this story arc making the fateful Jedi Purge the greatest nightmare of the clone troopers in heartbreaking fashion.

This trial evaluated the combination of Cabometyx with against Cabometyx alone in individuals with advanced or metastatic clear cell or non-clear cell renal cell carcinoma (RCC) who had previously shown progression on immune checkpoint inhibitor therapy.

To his excuse, Crosshair was also the only Bad Batch clone whose inhibitor chip activated while the others’ chips malfunctioned.

In September, Roche won FDA approval for Tecentriq Hybreza, the injectable version of its PD-L1 inhibitor Tecentriq.

Many CDK4/6 inhibitor resistant patients have now been reclassified as eligible for this therapy with the advent of a new biomarker designation, Her2 low.

One other type of drug, called a tyrosine kinase inhibitor, blocks an enzyme that’s needed for tumor cells to grow and divide.

Smad7 acts as an inhibitor of TGF-β signaling.

Thanks to the Warband Bank Distance Inhibitor, you can!

The study provides novel insights into the physiological role and mechanisms of p21 in HSCs during homeostasis independent of its conventional role as a cell cycle inhibitor.

Using a synthetic gingipains inhibitor, the researchers were able to reduce neuroinflammation by lowering the bacterial load of P. gingivalis.

A 2015 study verified its safety for use in humans, and in 2017 the inhibitor completed a clinical trial in human patients.

Actinomycin D, an inhibitor of RNA-dependent RNA polymerase, is a potent antibiotic with therapeutic utilities in infectious diseases and cancer.

And we think it's important also as we were to answer these types of questions for the field in general, because we are just at the beginning of these clinical experiments, combining a checkpoint inhibitor with a cell therapy as well.

Favipiravir is an oral RNA-dependent RNA polymerase inhibitor, and the drug is under investigation in many countries for the treatment of Covid-19.

In DME, an intravitreally administered plasma kallikrein inhibitor known as KVD001, completed a Phase 2 clinical trial in 2019.

It could also show us how Rex found other Clones out there, and how he helped them remove their own inhibitor chips.

Nicotinamide is a histone deacetylase inhibitor, so has the potential to reawaken not only cells that carry sleeping HIV, but also to activate other random genes in the cell, meaning that unintended effects may occur.