Interneurons

Recently, two types of neuropeptide-y expressing GABAergic interneurons have been described in detail, citation one of which translates synchronous activity of cholinergic interneurons into inhibition of principal neurons.

The corticospinal tract is a white matter motor pathway starting at the cerebral cortex that terminates on lower motor neurons and interneurons in the spinal cord.

Because interneurons require more energy compared to other neurons, they may be more susceptible to dying when they encounter the Alzheimer’s disease protein amyloid beta.

They showed that these enhanced interneurons, when transplanted into the abnormal brain of Alzheimer mice, can properly control the activity of excitatory cells and restore brain rhythms.

Interneurons present in the grey matter of the spinal cord Rexed laminae groups the grey matter in the spinal cord according to its function.

One target is a set of spinal interneurons that project to motor neurons controlling the arm muscles.

Such nonspiking neurons tend to be sensory neurons or interneurons, because they cannot carry signals long distances.

The interneurons excite the motor neurons, and if the excitation is strong enough, some of the motor neurons generate action potentials, which travel down their axons to the point where they make excitatory synaptic contacts with muscle cells.