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Ligase is an English word. Below you'll find 10+ example sentences showing how it's used in practice.

Rare word

Ligase in a sentence

Related words

Ligase | Ligases

Ligase meaning

Any of a group of enzymes that catalyze the binding of two molecules; synthetase.

Using Ligase

  • The main meaning on this page is: Any of a group of enzymes that catalyze the binding of two molecules; synthetase.
  • In the example corpus, ligase often appears in combinations such as: dna ligase, ubiquitin ligase.

Context around Ligase

  • Average sentence length in these examples: 24.4 words
  • Position in the sentence: 4 start, 1 middle, 5 end
  • Sentence types: 10 statements, 0 questions, 0 exclamations

Often before:

dna 6× ubiquitin 1× higher 1×

Often after:

using 1× creating 1× complex 1× works 1× concentration 1× activity 1×

Sentence patterns with Ligase

These short patterns come directly from the example sentences and show how the word is often embedded:

a dna ligase that closes 1× a higher ligase concentration to 1× as dna ligase iv may 1× by dna ligase using the 1× coli dna ligase 1× dna ligase is used 1× e3 ubiquitin ligase complex which 1× ligase can join 1×

Sentence openings and endings

Common sentence openings:

dna ligase is 1× hif is synthesized 1× it plays a 1× ligase can join 1× ligase works to 1× single strand breaks 1×

Common sentence endings:

and ligase activity 1× coli dna ligase 1× dna during replication 1× for rapid degradation 1× repair the dna 1× replicated dna molecule 1×

Words around Ligase

Just before it in the word index:

ligas 2 ligao 3 ligands 96 ligandrol 3 ligand 122 ligaments 83

Just after it in the word index:

ligases 7 ligate 2 ligated 2 ligating 2 ligation 15 ligations 3

Similar in corpus frequency:

aadi 14 aayush 14 abbottabad 14 aberdonian 14 abhi 14 aborting 14

Corpus analysis for Ligase

  • In this selection, "ligase" usually appears near the end of the sentence. The average example has 24.4 words, and this corpus slice is mostly made up of statements.
  • Around the word, dna, ubiquitin, higher, using, creating and complex stand out and add context to how "ligase" is used.
  • Recognizable usage signals include a dna ligase that closes and a higher ligase concentration to. That gives this page its own corpus information beyond isolated example sentences.
  • By corpus frequency, "ligase" sits close to words such as aadi, aayush and abbottabad, which helps place it inside the broader word index.

Example types with ligase

The same corpus examples are grouped by length and sentence type, making it easier to see the contexts in which the word appears:

Short example sentences

Topoisomerases and helicases Topoisomerases are enzymes with both nuclease and ligase activity. (12 words)

DNA ligase is used in both DNA repair and DNA replication (see Mammalian ligases ). (14 words)

Ligase works to fill these nicks in, thus completing the newly replicated DNA molecule. (14 words)

Longer example sentences

It plays a role in repairing single-strand breaks in duplex DNA in living organisms, but some forms (such as DNA ligase IV ) may specifically repair double-strand breaks (i.e. a break in both complementary strands of DNA). (39 words)

This step cuts out the DNA transposon, which is then ligated into a new target site; the process involves activity of a DNA polymerase that fills in gaps and of a DNA ligase that closes the sugar-phosphate backbone. (39 words)

Single-strand breaks are repaired by DNA ligase using the complementary strand of the double helix as a template, citation with DNA ligase creating the final phosphodiester bond to fully repair the DNA. (33 words)

Example sentences (10)

Single-strand breaks are repaired by DNA ligase using the complementary strand of the double helix as a template, citation with DNA ligase creating the final phosphodiester bond to fully repair the DNA.

DNA ligase is used in both DNA repair and DNA replication (see Mammalian ligases ).

HIF is synthesized consititutively, and hydroxylation of at least one of two critical proline residues mediates their interaction with the von Hippel Lindau E3 ubiquitin ligase complex, which targets them for rapid degradation.

It can also ligate blunt-ended DNA with much greater efficiency than E. coli DNA ligase.

It plays a role in repairing single-strand breaks in duplex DNA in living organisms, but some forms (such as DNA ligase IV ) may specifically repair double-strand breaks (i.e. a break in both complementary strands of DNA).

Ligase can join two complementary fragments of nucleic acid and repair single stranded breaks that arise in double stranded DNA during replication.

Ligase works to fill these nicks in, thus completing the newly replicated DNA molecule.

The absence of stably annealed ends also means that the ligation efficiency is lowered, requiring a higher ligase concentration to be used.

This step cuts out the DNA transposon, which is then ligated into a new target site; the process involves activity of a DNA polymerase that fills in gaps and of a DNA ligase that closes the sugar-phosphate backbone.

Topoisomerases and helicases Topoisomerases are enzymes with both nuclease and ligase activity.

Common combinations with ligase

These word pairs occur most frequently in English texts:

Frequently asked questions

How do you use "ligase" in a sentence?
An example: "Single-strand breaks are repaired by DNA ligase using the complementary strand of the double helix as a template, citation with DNA ligase creating the final phosphodiester bond to fully repair the DNA." This page contains 10+ example sentences with the word "ligase" from authentic English texts.
What does "ligase" mean?
Ligase means: Any of a group of enzymes that catalyze the binding of two molecules; synthetase.
How many example sentences with "ligase" are there?
Voorbeeldzinnen.info contains at least 10+ example sentences with "ligase", drawn from a database of millions of English sentences.