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On this page you'll find 10+ example sentences with Misfolded. Discover the meaning, how to use the word correctly in a sentence.

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Misfolded in a sentence

Related words

Misfolded | Misfolding | Misfold

Misfolded meaning

simple past and past participle of misfold

Using Misfolded

  • The main meaning on this page is: simple past and past participle of misfold
  • In the example corpus, misfolded often appears in combinations such as: misfolded proteins, of misfolded, misfolded alpha-synuclein.

Context around Misfolded

  • Average sentence length in these examples: 22.2 words
  • Position in the sentence: 7 start, 5 middle, 2 end
  • Sentence types: 13 statements, 1 questions, 0 exclamations

Often before:

same 1× instances 1×

Often after:

proteins 7× alpha 3× structure 1× copy 1× cellular 1× protein 1× form 1×

Sentence patterns with Misfolded

These short patterns come directly from the example sentences and show how the word is often embedded:

accumulation of misfolded proteins in 1× and or misfolded proteins are 1× does a misfolded protein do 1× found that misfolded alpha synuclein 1× into another misfolded copy 1× mass of misfolded proteins disrupts 1× prion a misfolded cellular protein 1× prions are misfolded proteins that 1×

Sentence openings and endings

Common sentence openings:

abnormal and or 1× als is a 1× both these sets 1× failure to fold 1× if overseer enzymes 1× most experts believe 1×

Common sentence endings:

and lymph tissue 1× another misfolded copy 1× causes cell death 1× disease in humans 1× in the nucleus 1× misfolded alpha synuclein 1×

Words around Misfolded

Just before it in the word index:

misfold 2 misfits 106 misfit 67 misfiring 28 misfires 24 misfired 28

Just after it in the word index:

misfolding 8 misfortunate 4 misfortune 189 misfortunes 81 misgav 8 misgender 10

Similar in corpus frequency:

aaronson 18 abai 18 abass 18 abatements 18 abdulfatah 18 abebe 18

Corpus analysis for Misfolded

  • In this selection, "misfolded" usually appears near the start of the sentence. The average example has 22.2 words, and this corpus slice is mostly made up of statements.
  • Around the word, same, instances, proteins, alpha and structure stand out and add context to how "misfolded" is used.
  • Recognizable usage signals include accumulation of misfolded proteins in and and or misfolded proteins are. That gives this page its own corpus information beyond isolated example sentences.
  • By corpus frequency, "misfolded" sits close to words such as aaronson, abai and abass, which helps place it inside the broader word index.

Example types with misfolded

The same corpus examples are grouped by length and sentence type, making it easier to see the contexts in which the word appears:

Short example sentences

So how does a misfolded protein do all of that damage? (11 words)

This mass of misfolded proteins disrupts neuronal cell function and causes cell death. (13 words)

The misfolded form of TDP-43 forms cytoplasmic inclusions in afflicted neurons, and is found depleted in the nucleus. (19 words)

Longer example sentences

If "overseer" enzymes note that residues are misfolded, proteins within the rER will re-add glucose residues so that other calreticulin/calnexin can bind to these proteins and prevent them from proceeding to the Golgi. (35 words)

ALS is a disease of the spinal cord, which can be triggered by the accumulation of misfolded proteins in motor neurons, the nerve cells in the spinal cord that drive movement. (31 words)

The researchers found that misfolded alpha-synuclein slowly spread to regions of the mouse brain associated with Parkinson’s disease, and dopamine-producing neurons started to die. (27 words)

Question examples

So how does a misfolded protein do all of that damage? (11 words)

Example sentences (14)

Prions are misfolded proteins that replicate by converting their properly folded counterparts, in their host, to the same misfolded structure they possess.

When a bad prion comes into contact with its normal self, it somehow forces it to turn into another misfolded copy.

ALS is a disease of the spinal cord, which can be triggered by the accumulation of misfolded proteins in motor neurons, the nerve cells in the spinal cord that drive movement.

Both these sets of mice performed similarly on all the tests to mice that didn’t receive any misfolded alpha-synuclein.

The researchers found that misfolded alpha-synuclein slowly spread to regions of the mouse brain associated with Parkinson’s disease, and dopamine-producing neurons started to die.

The researchers say the way the misfolded alpha-synuclein spreads in the brains of the mice, and the animals’ symptoms, closely mirrors the disease in humans.

Most experts believe the infectious agent is something called a prion, a misfolded cellular protein found in the nervous system and lymph tissue.

So how does a misfolded protein do all of that damage?

Advertentie

Abnormal and or misfolded proteins are degraded more rapidly either due to being targeted for destruction or due to being unstable.

Failure to fold into native structure generally produces inactive proteins, but in some instances misfolded proteins have modified or toxic functionality.

If "overseer" enzymes note that residues are misfolded, proteins within the rER will re-add glucose residues so that other calreticulin/calnexin can bind to these proteins and prevent them from proceeding to the Golgi.

The misfolded form of TDP-43 forms cytoplasmic inclusions in afflicted neurons, and is found depleted in the nucleus.

They also aid in the lysis and recycling of misfolded proteins that have begun to build up within the cell.

This mass of misfolded proteins disrupts neuronal cell function and causes cell death.

Advertentie

Common combinations with misfolded

These word pairs occur most frequently in English texts:

Frequently asked questions

How do you use "misfolded" in a sentence?
An example: "Prions are misfolded proteins that replicate by converting their properly folded counterparts, in their host, to the same misfolded structure they possess." This page contains 10+ example sentences with the word "misfolded" from authentic English texts.
What does "misfolded" mean?
Misfolded means: simple past and past participle of misfold
How many example sentences with "misfolded" are there?
Voorbeeldzinnen.info contains at least 10+ example sentences with "misfolded", drawn from a database of millions of English sentences.