Below you will find example sentences with "reverse transcriptase". The examples show how this phrase is used in natural context and which words often surround it.

Reverse Transcriptase in a sentence

Corpus data

  • Displayed example sentences: 20
  • Discovered as a combination around: reverse
  • Corpus frequency in the collocation scan: 5
  • Phrase length: 2 words
  • Average sentence length: 25.5 words

Words in this phrase

reverse transcriptase

Meanings of words in this phrase

  • reverse can mean: Opposite, contrary; going in the opposite direction. Frequent word
  • transcriptase can mean: A polymerase that catalyzes the transcription of DNA to RNA. Rare word

Sentence profile

  • Phrase position: 4 start, 13 middle, 3 end
  • Sentence types: 20 statements, 0 questions, 0 exclamations

Usage patterns

These patterns show short text windows around the phrase in the example sentences:

action of reverse transcriptase has led 1× all the reverse transcriptase synthesizes viral 1× along with reverse transcriptase into bacteria 1× and the reverse transcriptase quickly mutate 1× biology details reverse transcriptase is commonly 1× by the reverse transcriptase acts as 1× catalyzed by reverse transcriptase recombination between 1× enzymes protease reverse transcriptase and integrase 1×

Sentence openings and endings

Common sentence openings:

an improved knowledge 1× by inserting eukaryotic 1× first of all 1× for example the 1× however these drugs 1× in eukaryotes self 1×

Common sentence endings:

an rna intermediate 1× an rna template 1× and integrase 1 1× block reverse transcriptase 1× complementary dna strand 1× dna to rna 1×

Context words

These words often appear near this phrase in the example sentences:

rna 15× dna 12× genome 7× viral 6× citation 4× gene 4× molecules 4× technique 3× pcr 3× template 3× transcribed 3× recombination 3×

Phrases around this combination

Just before it in the phrase index:

revenue guidance revenue growth revenue generated revenue forecast reuters reported reuters poll

Just after it in the phrase index:

review board review process revolutionary guards ribbon cutting rice farmers rice prices

Corpus analysis

  • The phrase "reverse transcriptase" has 2 words and usually appears in the middle in these examples. The average sentence has 25.5 words and is mostly made up of statements.
  • Around this phrase, patterns and context words such as action of reverse transcriptase has led, all the reverse transcriptase synthesizes viral, rna, dna and genome stand out.

Example types with reverse transcriptase

This selection groups the examples by length and sentence type, making usage of the full phrase easier to scan:

Short example sentences

Process of reverse transcription Reverse transcriptase creates single-stranded DNA from an RNA template. (14 words)

Therefore, the primer and reverse transcriptase must be relocated to 3’ end of viral RNA. (15 words)

Reverse transcriptase converted this edited RNA back into DNA so it could be incorporated in the genome. (17 words)

Longer example sentences

The fact that the PBS is located near the 5’ terminus of viral RNA is unusual because reverse transcriptase synthesize DNA from 3’ end of the primer in the 5’ to 3’ direction (with respect to the RNA template). (39 words)

It is unknown how often such mixed packaging occurs under natural conditions. citation Bonhoeffer et al. citation suggested that template switching by the reverse transcriptase acts as a repair process to deal with breaks in the ssRNA genome. (38 words)

Upon entry into the target cell, the viral RNA genome is converted (reverse transcribed) into double-stranded DNA by a virally encoded reverse transcriptase that is transported along with the viral genome in the virus particle. (36 words)

Example sentences (20)

This approach is more commonly associated with the inhibition of reverse transcriptase (RNA to DNA) than with "normal" transcriptase (DNA to RNA).

Molecular biology details Reverse transcriptase is commonly used in research to apply the polymerase chain reaction technique to RNA in a technique called reverse transcription polymerase chain reaction (RT-PCR).

Process of reverse transcription Reverse transcriptase creates single-stranded DNA from an RNA template.

Upon entry into the target cell, the viral RNA genome is converted (reverse transcribed) into double-stranded DNA by a virally encoded reverse transcriptase that is transported along with the viral genome in the virus particle.

Upon infection and replication catalyzed by reverse transcriptase, recombination between the two genomes can occur. citation citation Recombination occurs as the single-strand (+)RNA genomes are reverse transcribed to form DNA.

An improved knowledge of the action of reverse transcriptase has led to better nucleoside analogues to treat HIV infections.

By inserting eukaryotic mRNA for insulin production along with reverse transcriptase into bacteria, the mRNA could be inserted into the prokaryote's genome.

First of all, the reverse transcriptase synthesizes viral DNA from viral RNA, and then from newly made complementary DNA strand.

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For example, the gag gene is translated into molecules of the capsid protein, the pol gene is translated into molecules of reverse transcriptase, and the env gene is translated into molecules of the envelope protein.

However these drugs can quickly become ineffective due to the fact that the gene sequences that code for the protease and the reverse transcriptase quickly mutate.

Industrial drugs that are designed as protease and reverse transcriptase inhibitors are made such that they target specific sites and sequences within their respective enzymes.

In eukaryotes Self-replicating stretches of eukaryotic genomes known as retrotransposons utilize reverse transcriptase to move from one position in the genome to another via an RNA intermediate.

It is unknown how often such mixed packaging occurs under natural conditions. citation Bonhoeffer et al. citation suggested that template switching by the reverse transcriptase acts as a repair process to deal with breaks in the ssRNA genome.

Researchers have gone further and developed inhibitors that do not look like nucleosides, but can still block reverse transcriptase.

Reverse transcriptase converted this edited RNA back into DNA so it could be incorporated in the genome.

Strand switching (copy-choice recombination) by reverse transcriptase could generate an undamaged copy of genomic DNA from two damaged ssRNA genome copies.

The classical PCR technique can be applied only to DNA strands, but, with the help of reverse transcriptase, RNA can be transcribed into DNA, thus making PCR analysis of RNA molecules possible.

The fact that the PBS is located near the 5’ terminus of viral RNA is unusual because reverse transcriptase synthesize DNA from 3’ end of the primer in the 5’ to 3’ direction (with respect to the RNA template).

There are two strands of RNA within the cell that have three enzymes: protease, reverse transcriptase, and integrase (1).

Therefore, the primer and reverse transcriptase must be relocated to 3’ end of viral RNA.

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