View example sentences, synonyms and word forms for Refractory.

Refractory

Refractory meaning

Obstinate and unruly; strongly opposed to something. | Not affected by great heat. | Resistant to treatment; not responding adequately to therapy.

Example sentences (20)

Additionally, in September, we announced that the FDA granted Fast Track designation for KT-333 for the treatment of relapsed/refractory cutaneous T-cell lymphoma and relapsed/refractory peripheral T-cell cell lymphoma.

Seven Refractories, the Divača-based maker of refractory concrete and plugs for blast furnaces, will get a new owner in RHI Magnesita, the Austrian producer of refractory materials, in a deal reportedly valued at €93 million.

An increased infusion of the hormone oxytocin during ejaculation is believed to be chiefly responsible for the refractory period, and the amount by which oxytocin is increased may affect the length of each refractory period.

The chamber is typically lined with refractory materials such as a hard castable refractory ceramic or a soft ceramic thermal blanket (ex: Kaowool).

And it is not just perfect for pizza, you can reheat croissants for your sweet breakfast or bake pies, biscuits and pastries directly on the refractory stone.

Cytopenias and infections were manageable and comparable to the experience with autologous CAR T therapies in patients with relapsed/refractory LBCL.

However, Merck defended its drug, insisting that the data demonstrated significant clinical benefits for adults with refractory or unexplained chronic cough.

I don't have the details of specific types of markers we're looking at in these specific indications, but they're all very much in the relapse refractory setting.

It is expected that a total of 186 women with platinum-resistant/refractory ovarian cancer are going to be randomized to receive one of the above treatment arms.

Our data support the strategy of early combined use the ECMO to treat severe ARDS for acute respiratory distress syndrome and refractory lung failure and is a prime example of our hit early hit heart treatment philosophy.

Our ISAC platform brings a novel mechanism with the potential to address refractory and recurrent disease to the treatment of HER2+ cancers and BDC-1001 has demonstrated promise.

Rigel Pharma has 2 FDA-approved drugs: Tavalisse for chronic immune thrombocytopenia (ITP) and Rezlidhia for relapsed or refractory AML with susceptible IDH1 mutation.

The key value proposition of Ensifentrine is that it has a novel mechanism that can offer additional therapeutic options for patients who are refractory on bronchodilators and steroids.

Turning to Slide 14, our GPRC5D targeting CAR-T is a potential first-in-class agent in relapse or refractory multiple myeloma.

REPL intends to initiate a confirmatory study comparing RP1 plus nivolumab against the physician's choice in the PD1-refractory group of patients with melanoma, with the hope of securing an accelerated approval while that trial is being conducted.

Because we will study both the relapsed refractory setting as well as the first line setting.

Loxo Oncology at Lilly is preparing to initiate a global, randomized, superiority Phase 3 clinical trial to study LOXO-305 versus currently available covalent BTK inhibitors in BTK treatment naïve patients with relapsed-refractory MCL.

No drug on top of, so these are again going to be refractory patients that have a certain seizure count over and above what they are currently on.

To date, only 2 CAR-T therapies - Gilead's () Yescarta and Novartis' Kymriah - have been approved, both for relapsed/refractory Diffuse Large B-Cell Lymphoma ("DLBCL").

XPOVIO is also approved by the FDA for treating adult patients with relapsed or refractory diffuse large B-cell lymphoma.