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On this page you'll find 10+ example sentences with Topoisomerase. Discover the meaning, how to use the word correctly in a sentence.

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Topoisomerase in a sentence

Topoisomerase meaning

Any of several enzymes that affect the topology of DNA, especially ones that relax supercoiling.

Using Topoisomerase

  • The main meaning on this page is: Any of several enzymes that affect the topology of DNA, especially ones that relax supercoiling.
  • In the example corpus, topoisomerase often appears in combinations such as: topoisomerase ii, the topoisomerase, of topoisomerase.

Context around Topoisomerase

  • Average sentence length in these examples: 19 words
  • Position in the sentence: 2 start, 6 middle, 2 end
  • Sentence types: 10 statements, 0 questions, 0 exclamations

Often before:

target 1×

Often after:

inhibitors 1× enzymes 1×

Sentence patterns with Topoisomerase

These short patterns come directly from the example sentences and show how the word is often embedded:

activity of topoisomerase ii and 1× agents or topoisomerase inhibitors 1× by the topoisomerase enzymes 1× domains of topoisomerase ia topoisomerase 1× gyrase or topoisomerase iv can 1× of the topoisomerase ii in 1× target whereas topoisomerase iv is 1× that target topoisomerase ii can 1×

Sentence openings and endings

Common sentence openings:

drugs that target 1× finally mutations at 1× for many gram 1× the most common 1× the second group 1× the stress caused 1×

Common sentence endings:

bound to dna 1× cannot unwind properly 1× gram positive bacteria 1× intact enzyme domains 1× into two groups 1× or topoisomerase inhibitors 1×

Words around Topoisomerase

Just before it in the word index:

topography 204 topographies 2 topographically 9 topographical 52 topographic 64 topographer 2

Just after it in the word index:

topol 11 topolino 2 topological 287 topologically 22 topologie 3 topologies 41

Similar in corpus frequency:

aanholt 13 aardwolf 13 abati 13 abbeville 13 abcc 13 abcon 13

Corpus analysis for Topoisomerase

  • In this selection, "topoisomerase" usually appears in the middle of the sentence. The average example has 19 words, and this corpus slice is mostly made up of statements.
  • Around the word, target, inhibitors and enzymes stand out and add context to how "topoisomerase" is used.
  • Recognizable usage signals include activity of topoisomerase ii and and agents or topoisomerase inhibitors. That gives this page its own corpus information beyond isolated example sentences.
  • By corpus frequency, "topoisomerase" sits close to words such as aanholt, aardwolf and abati, which helps place it inside the broader word index.

Example types with topoisomerase

The same corpus examples are grouped by length and sentence type, making it easier to see the contexts in which the word appears:

Short example sentences

Then, topoisomerase 1 tries to repair the damage. (8 words)

Drugs that target topoisomerase II can be divided into two groups. (11 words)

The topoisomerase II poisons cause increased levels enzymes bound to DNA. (11 words)

Longer example sentences

This modification, coupled with the constant action of the topoisomerase II in the bacterial cell, leads to DNA fragmentation via the nucleasic activity of the intact enzyme domains. (28 words)

This structure is also found in the catalytic domains of topoisomerase Ia, topoisomerase II, the OLD-family nucleases and DNA repair proteins related to the RecR protein. (27 words)

The second group, catalytic inhibitors, are drugs that block the activity of topoisomerase II, and therefore prevent DNA synthesis and translation because the DNA cannot unwind properly. (27 words)

Example sentences (10)

This structure is also found in the catalytic domains of topoisomerase Ia, topoisomerase II, the OLD-family nucleases and DNA repair proteins related to the RecR protein.

Drugs that target topoisomerase II can be divided into two groups.

Finally, mutations at key sites in DNA gyrase or topoisomerase IV can decrease their binding affinity to quinolones, decreasing the drugs' effectiveness.

For many gram-negative bacteria, DNA gyrase is the target, whereas topoisomerase IV is the target for many gram-positive bacteria.

The most common secondary neoplasm is secondary acute myeloid leukemia, which develops primarily after treatment with alkylating agents or topoisomerase inhibitors.

Then, topoisomerase 1 tries to repair the damage.

The second group, catalytic inhibitors, are drugs that block the activity of topoisomerase II, and therefore prevent DNA synthesis and translation because the DNA cannot unwind properly.

The stress caused by this effect is in part aided by the topoisomerase enzymes.

The topoisomerase II poisons cause increased levels enzymes bound to DNA.

This modification, coupled with the constant action of the topoisomerase II in the bacterial cell, leads to DNA fragmentation via the nucleasic activity of the intact enzyme domains.

Common combinations with topoisomerase

These word pairs occur most frequently in English texts:

Frequently asked questions

How do you use "topoisomerase" in a sentence?
An example: "This structure is also found in the catalytic domains of topoisomerase Ia, topoisomerase II, the OLD-family nucleases and DNA repair proteins related to the RecR protein." This page contains 10+ example sentences with the word "topoisomerase" from authentic English texts.
What does "topoisomerase" mean?
Topoisomerase means: Any of several enzymes that affect the topology of DNA, especially ones that relax supercoiling.
How many example sentences with "topoisomerase" are there?
Voorbeeldzinnen.info contains at least 10+ example sentences with "topoisomerase", drawn from a database of millions of English sentences.