View example sentences and word forms for Uncoating.
Uncoating meaning
A process in which the viral capsid of a virus is removed, leading to the release of the viral genomic nucleic acid.
Example sentences (4)
Chemical properties The viral particle must be metastable so that interactions can be reversed readily when entering and uncoating a new host cell.
Delivery of the genome is also important by specific binding to external receptors of the host cell, transmission of specific signals that induce uncoating of the genome, and induction of fusion with host cell membranes.
The virus must go through a sequence of steps to do this, beginning with binding to a specific " receptor " molecule on the surface of the host cell and ending with the virus "uncoating" inside the cell and releasing its contents.
Uncoating yields a transcriptionally active 470S core particle which is composed of two major proteins VP7 and VP3, and the three minor proteins VP1, VP4 and VP6 in addition to the dsRNA genome.