On this page you'll find 10+ example sentences with Vhl. Discover how to use the word correctly in a sentence.
Vhl in a sentence
Using Vhl
- In the example corpus, vhl often appears in combinations such as: vhl disease, of vhl, in vhl.
Context around Vhl
- Average sentence length in these examples: 19.5 words
- Position in the sentence: 6 start, 5 middle, 2 end
- Sentence types: 13 statements, 0 questions, 0 exclamations
Corpus analysis for Vhl
- In this selection, "vhl" usually appears near the start of the sentence. The average example has 19.5 words, and this corpus slice is mostly made up of statements.
- Around the word, diagnose, lindau, epidemiology, disease, gene and syndrome stand out and add context to how "vhl" is used.
- Recognizable usage signals include 40 of vhl disease presents and 59 of vhl disease and. That gives this page its own corpus information beyond isolated example sentences.
- By corpus frequency, "vhl" sits close to words such as aanand, abcd and abdurrahman, which helps place it inside the broader word index.
Example types with vhl
The same corpus examples are grouped by length and sentence type, making it easier to see the contexts in which the word appears:
VHL protein The regulation of HIF1α by pVHL. (8 words)
Genetic diagnosis is also useful in VHL disease diagnosis. (9 words)
Belzutifan is used to treat adults with Von Hippel-Lindau (VHL) syndrome. (12 words)
A lack of this protein allows tumors characteristic of von Hippel–Lindau syndrome to develop. citation citation Approximately 20% of cases of VHL disease are found in individuals without a family history, known as de novo mutations. (37 words)
As all the tumours associated with VHL disease can be found sporadically, at least two tumours must be identified to diagnose VHL disease in a person without a family history. (30 words)
Pathogenesis The disease is caused by mutations of the von Hippel–Lindau tumor suppressor (VHL) gene on the short arm of chromosome 3 (3p25-26). (25 words)
Example sentences (13)
As all the tumours associated with VHL disease can be found sporadically, at least two tumours must be identified to diagnose VHL disease in a person without a family history.
In low oxygen conditions or in cases of VHL disease where the VHL gene is mutated, pVHL does not bind to HIF1α.
Spinal hemangioblastomas are found in 13-59% of VHL disease and are specific because 80% are found in VHL disease.
Belzutifan is used to treat adults with Von Hippel-Lindau (VHL) syndrome.
A lack of this protein allows tumors characteristic of von Hippel–Lindau syndrome to develop. citation citation Approximately 20% of cases of VHL disease are found in individuals without a family history, known as de novo mutations.
Approximately 40% of VHL disease presents with CNS hemangioblastomas and they are present in around 60-80%.
Epidemiology VHL disease has an incidence of one in 36,000 births.
Genetic diagnosis is also useful in VHL disease diagnosis.
In hereditary VHL, disease techniques such as southern blotting and gene sequencing can be used to analyse DNA and identify mutations.
In individuals with a family history of VHL disease, one hemangioblastoma, pheochromocytoma or renal cell carcinoma may be sufficient to make a diagnosis.
In VHL disease, genetic mutations cause alterations to the pVHL protein, usually to the HIF1α binding site.
Pathogenesis The disease is caused by mutations of the von Hippel–Lindau tumor suppressor (VHL) gene on the short arm of chromosome 3 (3p25-26).
VHL protein The regulation of HIF1α by pVHL.
Common combinations with vhl
These word pairs occur most frequently in English texts:
- vhl disease 12×
- of vhl 5×
- in vhl 3×
- vhl gene 2×