Nucleosome is an English word. Below you'll find 10+ example sentences showing how it's used in practice.
Nucleosome meaning
Any of the subunits that repeat in chromatin; a coil of DNA surrounding a core of eight histones.
Using Nucleosome
- The main meaning on this page is: Any of the subunits that repeat in chromatin; a coil of DNA surrounding a core of eight histones.
- In the example corpus, nucleosome often appears in combinations such as: the nucleosome, nucleosome core, are nucleosome.
Context around Nucleosome
- Average sentence length in these examples: 21.8 words
- Position in the sentence: 8 start, 7 middle, 5 end
- Sentence types: 20 statements, 0 questions, 0 exclamations
Corpus analysis for Nucleosome
- In this selection, "nucleosome" usually appears near the start of the sentence. The average example has 21.8 words, and this corpus slice is mostly made up of statements.
- Around the word, dependent, reduced, changes, core, structure and depleted stand out and add context to how "nucleosome" is used.
- Recognizable usage signals include 20 different nucleosome core particles and atp dependent nucleosome remodeling a. That gives this page its own corpus information beyond isolated example sentences.
- By corpus frequency, "nucleosome" sits close to words such as aaj, abn and aboriginals, which helps place it inside the broader word index.
Example types with nucleosome
The same corpus examples are grouped by length and sentence type, making it easier to see the contexts in which the word appears:
Thus nucleosome positioning is to some degree inheritable. (8 words)
The basic structural unit of chromatin is the nucleosome. (9 words)
Print. Partial DNAse digestion of chromatin reveals its nucleosome structure. (10 words)
The work shows that the transcription start site for genes expressed in a particular tissue, are nucleosome depleted while, the same set of genes in other tissue where they are not expressed, are nucleosome bound. (35 words)
H2A can be replaced by H2AZ (which leads to reduced nucleosome stability) or H2AX (which is associated with DNA repair and T cell differentiation), whereas the inactive X chromosomes in mammals are enriched in macroH2A. (35 words)
The human alpha-satellite palindromic DNA critical to achieving the 1997 nucleosome crystal structure was developed by the Bunick group at Oak Ridge National Laboratory in Tennessee. citation Large-scale production of palindrome DNA fragments. (35 words)
Example sentences (20)
The work shows that the transcription start site for genes expressed in a particular tissue, are nucleosome depleted while, the same set of genes in other tissue where they are not expressed, are nucleosome bound.
Asymmetries in the nucleosome core particle at 2.5 A resolution.
ATP-dependent nucleosome remodeling A number of distinct reactions are associated with the term ATP-dependent chromatin remodeling.
H2A can be replaced by H2AZ (which leads to reduced nucleosome stability) or H2AX (which is associated with DNA repair and T cell differentiation), whereas the inactive X chromosomes in mammals are enriched in macroH2A.
However, even in chromosomal regions that were not associated with transcriptional changes, nucleosome repositioning was observed, suggesting that the covering and uncovering of transcriptional DNA does not necessarily produce a transcriptional event.
In 2012, Beena Pillai's laboratory has demonstrated that nucleosome sliding is one of the possible mechanism for large scale tissue specific expression of genes.
In addition to the core histones, there is the linker histone, H1, which contacts the exit/entry of the DNA strand on the nucleosome.
Modulating nucleosome structure Eukaryotic genomes are ubiquitously associated into chromatin; however, cells must spatially and temporally regulate specific loci independently of bulk chromatin.
Nucleosome positions are controlled by three major contributions: First, the intrinsic binding affinity of the histone octamer depends on the DNA sequence.
Print. Partial DNAse digestion of chromatin reveals its nucleosome structure.
Protein interactions within the nucleosome The core histone proteins contains a characteristic structural motif termed the "histone fold," which consists of three alpha-helices (α1-3) separated by two loops (L1-2).
Second, the nucleosome can be displaced or recruited by the competitive or cooperative binding of other protein factors.
The basic structural unit of chromatin is the nucleosome.
The human alpha-satellite palindromic DNA critical to achieving the 1997 nucleosome crystal structure was developed by the Bunick group at Oak Ridge National Laboratory in Tennessee. citation Large-scale production of palindrome DNA fragments.
The nucleosome core particle, together with histone H1, is known as a chromatosome.
The organization of the DNA that is achieved by the nucleosome cannot fully explain the packaging of DNA observed in the cell nucleus.
These play a dual role of a site of recognition by many proteins and as a sink for torsional stress from RNA polymerase or nucleosome binding.
The structures of over 20 different nucleosome core particles have been solved to date, citation including those containing histone variants and histones from different species.
Thus nucleosome positioning is to some degree inheritable.
X-ray diffraction analysis of crystals containing twofold symmetric nucleosome core particles.
Common combinations with nucleosome
These word pairs occur most frequently in English texts: