Explore Oncogene through 10+ example sentences from English, with an explanation of the meaning and related words like gene or cistron. Ideal for language learners, writers and word enthusiasts.
Oncogene meaning
Any gene that contributes to the conversion of a normal cell into a cancerous cell when mutated or expressed at high levels.
Using Oncogene
- The main meaning on this page is: Any gene that contributes to the conversion of a normal cell into a cancerous cell when mutated or expressed at high levels.
- Useful related words include: transforming gene, gene, cistron, factor.
- In the example corpus, oncogene often appears in combinations such as: the oncogene, oncogene of, an oncogene.
Context around Oncogene
- Average sentence length in these examples: 20.8 words
- Position in the sentence: 2 start, 7 middle, 2 end
- Sentence types: 11 statements, 0 questions, 0 exclamations
Corpus analysis for Oncogene
- In this selection, "oncogene" usually appears in the middle of the sentence. The average example has 20.8 words, and this corpus slice is mostly made up of statements.
- Around the word, proto, true, activation, theory and mutations stand out and add context to how "oncogene" is used.
- Recognizable usage signals include a proto oncogene c kit and a proto oncogene is also. That gives this page its own corpus information beyond isolated example sentences.
- By corpus frequency, "oncogene" sits close to words such as aami, aat and abada, which helps place it inside the broader word index.
Example types with oncogene
The same corpus examples are grouped by length and sentence type, making it easier to see the contexts in which the word appears:
The resultant protein encoded by an oncogene is termed oncoprotein. (10 words)
In some cases, a proto-oncogene is also activated by a chromosomal mutation. (13 words)
Oncogene mutations, in contrast, generally involve a single allele because they are gain-of-function mutations. (16 words)
Michael Bishop and Harold Varmus showed that the oncogene of Rous sarcoma virus is in fact not specific to the virus but is contained in the genome of healthy animals of many species. (33 words)
Oncoproteins are any proteins coded by an oncogene and they play an important role in the regulation or synthesis of proteins linked to tumorigenic cell growth. (26 words)
The loss of these genes may be even more important than proto-oncogene/ oncogene activation for the formation of many kinds of human cancer cells. (25 words)
Example sentences (11)
The loss of these genes may be even more important than proto-oncogene/ oncogene activation for the formation of many kinds of human cancer cells.
The oncovirus can switch this pre-existing benign proto-oncogene on, turning it into a true oncogene that causes cancer.
In some cases, a proto-oncogene is also activated by a chromosomal mutation.
Experiments performed by Dr. G. Steve Martin of the University of California, Berkeley demonstrated that the Src was indeed the oncogene of the virus.
For this discovery, proving Todaro and Heubner's "oncogene theory", Bishop and Varmus were awarded the Nobel Prize in Physiology or Medicine in 1989.
Michael Bishop and Harold Varmus showed that the oncogene of Rous sarcoma virus is in fact not specific to the virus but is contained in the genome of healthy animals of many species.
Oncogene mutations, in contrast, generally involve a single allele because they are gain-of-function mutations.
Oncoproteins are any proteins coded by an oncogene and they play an important role in the regulation or synthesis of proteins linked to tumorigenic cell growth.
Recent evidence also indicates that several genes (including the proto-oncogene c-myc ) have G-quadruplex motifs as potential regulatory signals.
The resultant protein encoded by an oncogene is termed oncoprotein.
This growth factor receptor is called c-kit and is produced by a proto-oncogene (c-kit).
Common combinations with oncogene
These word pairs occur most frequently in English texts:
- the oncogene 2×
- oncogene of 2×
- an oncogene 2×