Selectivity in a sentence

Enabled by HotSpot's proprietary Smart AllosteryTM platform, HST-1011 is designed with tight binding, low nanomolar potency, a slow dissociation rate from the target to enable sustained pharmacology, and greater selectivity for CBL-B relative to C-CBL.

Medicinal chemists work to modify the chemical structure of the leads to improve their potency, selectivity, and drug-likeness.

The breakthrough was made during early experiments which tested the compound both in vitro and in vivo, with data suggesting its in-vitro potency and selectivity to target, as well as its in-vivo availability in blood, shows excellent drug-like potential.

The π-electron system of the styrene substrate was found to form C-H···π interactions with in the catalyst, which enabled over the stereochemical selectivity of the reaction.

But the level of selectivity is exaggerated in these business and finance groups, to the extent that it’s almost comical how tough – and seemingly arbitrary – it is to get in.

The selectivity is achieved by the modulation of the nickel catalyst by ruthenium- or iridium-based photocatalysts with different reductive potentials and the presence of heat in a "stop flow" reactor.

This was based on studies of bachelor’s degree holders 10 years after they completed their undergraduate degrees based on the school’s selectivity ratings.

According to the Managing Director of the agency, Capt. Fola Akinkuotu, the inspection exercise cut across sensitivity, selectivity, signal to noise ratio, power output as well as range covered by the radios.

Future studies will seek to determine if the selectivity profile of AK-01 can improve efficacy while limiting toxicity risks to a manageable level.

Selectivity by any means, dubious selective schools tests or high fees, breeds inequity in education, and society generally.

The results, says Hoorfar, indicate an inexpensive device that has a high-level of sensitivity, selectivity and durability.

The selectivity of the drug means it does not cause the severe side effects associated with many traditional cancer treatments, and none of the patients with TRK fusions had to quit the study because of a drug-induced side effect, they said.

This has allowed them to have a bit more selectivity in which players they target on the transfer market.

This kind of kinetic selectivity ensures the effectiveness of the drug while limiting side effects.

As a result, the selectivity of Johns Hopkins University has also increased.

At the cost of an extra frequency converter stage, the superheterodyne receiver provides superior selectivity and sensitivity compared with simpler designs.

Data selection controversy There is some controversy over selectivity in Millikan's use of results from his second experiment measuring the electron charge.

First, it is easier and less expensive to get high selectivity at a lower frequency.

For the same bandwidth, a tuned circuit at a lower frequency needs a lower Q. Stated another way, for the same filter technology, a higher center frequency will take more IF filter stages to achieve the same selectivity bandwidth.

Hypercapnia best explains the selectivity of the extinction, but anoxia and euxinia probably contributed to the high mortality of the event.