Explore Sibm through 10+ example sentences from English. Ideal for language learners, writers and word enthusiasts.
Sibm in a sentence
Using Sibm
- In the example corpus, sibm often appears in combinations such as: sibm is, of sibm, sibm sibm.
Context around Sibm
- Average sentence length in these examples: 26.1 words
- Position in the sentence: 2 start, 11 middle, 1 end
- Sentence types: 14 statements, 0 questions, 0 exclamations
Corpus analysis for Sibm
- In this selection, "sibm" usually appears in the middle of the sentence. The average example has 26.1 words, and this corpus slice is mostly made up of statements.
- Around the word, eventually, confirmed, treat, patients, weakness and makes stand out and add context to how "sibm" is used.
- Recognizable usage signals include and eventually sibm is confirmed and aspects of sibm sibm is. That gives this page its own corpus information beyond isolated example sentences.
- By corpus frequency, "sibm" sits close to words such as aaronson, abai and abass, which helps place it inside the broader word index.
Example types with sibm
The same corpus examples are grouped by length and sentence type, making it easier to see the contexts in which the word appears:
The understanding of sIBM is slowly maturing and evolving. (9 words)
It may have different root causes unrelated to either polymyositis or sIBM. (12 words)
In 2016, Novartis intends to apply for FDA approval to treat sIBM patients with bimagrumab BYM338. (16 words)
This important advance should help develop a new screening technique for IBM and may provide clues in terms of a therapeutic approach citation Genetic aspects of sIBM sIBM is not inherited and is not passed on to the children of IBM patients. (42 words)
In people with sIBM, the muscle cells display “flags” telling the immune system that they are infected or damaged (the muscles ubiquitously express MHC class I antigens) and this immune process leads to the death of muscle cells. (38 words)
Therefore, one focus of treatment should be the improvement of aerobic capacity. citation Patients with sIBM usually eventually need to resort to a cane or a walker and in most cases, a wheelchair eventually becomes a necessity. (37 words)
Example sentences (14)
A course of prednisone is typically completed with no improvement and eventually sIBM is confirmed. sIBM weakness comes on over months or years and progresses steadily, whereas polymyositis has an onset of weeks or months.
This important advance should help develop a new screening technique for IBM and may provide clues in terms of a therapeutic approach citation Genetic aspects of sIBM sIBM is not inherited and is not passed on to the children of IBM patients.
Because sIBM makes the leg muscles weak and unstable, patients are very vulnerable to serious injury from tripping or falling down.
Diagnosis Elevated creatine kinase CK levels (at most ~10 times normal) are typical in sIBM but patients can also present with normal CK levels.
In 2016, Novartis intends to apply for FDA approval to treat sIBM patients with bimagrumab BYM338.
In people with sIBM, the muscle cells display “flags” telling the immune system that they are infected or damaged (the muscles ubiquitously express MHC class I antigens) and this immune process leads to the death of muscle cells.
It may have different root causes unrelated to either polymyositis or sIBM.
One confusing aspect is that medications that lower the immune response do not improve sIBM symptoms, as would be expected in the case of an autoimmune disorder.
Respiratory muscle weakness can sometimes eventuate." citation Causes The causes of sIBM are unknown, though it is likely that the disorder results from the interaction of a number of factors, both genetic and environmental.
There are two types: sporadic inclusion body myositis (sIBM), which is more common, and hereditary inclusion body myopathy (hIBM).
Therefore, one focus of treatment should be the improvement of aerobic capacity. citation Patients with sIBM usually eventually need to resort to a cane or a walker and in most cases, a wheelchair eventually becomes a necessity.
The understanding of sIBM is slowly maturing and evolving.
Treatment There is no standard course of treatment to slow or stop the progression of the disease. sIBM patients do not reliably respond to the anti-inflammatory, immunosuppressant, or immunomodulatory drugs that have been tried.
Two other disorders were also known to display muscle inflammation, and sIBM was classified along with them.
Common combinations with sibm
These word pairs occur most frequently in English texts:
- sibm is 3×
- of sibm 3×
- sibm sibm 2×
- sibm patients 2×
- with sibm 2×