Egfr is an English word of 4 letters. Below you'll find 10+ example sentences showing how it's used in practice.
Egfr in a sentence
Egfr meaning
Initialism of epidermal growth factor receptor.
Using Egfr
- The main meaning on this page is: Initialism of epidermal growth factor receptor.
- In the example corpus, egfr often appears in combinations such as: or egfr, egfr mutations, egfr and.
Context around Egfr
- Average sentence length in these examples: 27 words
- Position in the sentence: 2 start, 7 middle, 5 end
- Sentence types: 14 statements, 0 questions, 0 exclamations
Corpus analysis for Egfr
- In this selection, "egfr" usually appears in the middle of the sentence. The average example has 27 words, and this corpus slice is mostly made up of statements.
- Around the word, common, cancer, anti, ex19del, l858r and mutations stand out and add context to how "egfr" is used.
- Recognizable usage signals include adjustment in egfr calculations and decline in egfr over the. That gives this page its own corpus information beyond isolated example sentences.
- By corpus frequency, "egfr" sits close to words such as aav, abdicating and abductor, which helps place it inside the broader word index.
Example types with egfr
The same corpus examples are grouped by length and sentence type, making it easier to see the contexts in which the word appears:
EGFR ex19del or EGFR L858R mutations are the most common EGFR mutations. (12 words)
Between 1996 and 2008 there was a trend to initiate dialysis at progressively higher estimated GFR, eGFR. (17 words)
The authors have found the promising potential of this peptide as an intracellular delivery vehicle directed to EGFR-positive cells. (20 words)
The most common mechanism of acquired resistance to first-line treatment with first-and second-generation EGFR-TKI is the T790M mutation, with approximately 30 to 60 percent of patients whose disease progresses acquiring the mutation. (36 words)
They then tweaked this section so it binds to a human protein called EGFR, which is found on the outside of some cells, again using AlphaFold to work out the effects of the tweaks. (34 words)
Mutational burdens were higher among patients with a history of smoking, who comprised more than three-quarters of those in the study, and lower among those without an alteration of the gene EGFR. (33 words)
Example sentences (14)
EGFR ex19del or EGFR L858R mutations are the most common EGFR mutations.
Checkpoint sees this as a potential new treatment for patients with EGFR mutation-positive non-small cell lung cancer as olafertinib is a third-generation epidermal growth factor receptor or EGFR inhibitor.
At the presentation, we're really focusing on eGFR data right now, which as you point out was very, very good function for our first set of patients.
In the ongoing study, the original three cohorts included patients with non-small cell lung cancer, EGFR wild type, gastric and gastroesophageal junction adenocarcinoma and pancreatic hepatocellular and biliary tract cancers respectively.
The drug works by binding to the EGFR protein and blocking its activity, essentially locking out the receptor telling cancer cells to grow.
They then tweaked this section so it binds to a human protein called EGFR, which is found on the outside of some cells, again using AlphaFold to work out the effects of the tweaks.
In response to Nkinsi’s calls, in 2020 UW Medicine announced it would transition away from the use of race adjustment in eGFR calculations.
Retrospective subset analyses across several randomized clinical trials were conducted to investigate the role of mutations on the clinical effects of anti-EGFR-directed monoclonal antibodies (panitumumab or cetuximab).
Mutational burdens were higher among patients with a history of smoking, who comprised more than three-quarters of those in the study, and lower among those without an alteration of the gene EGFR.
The most common mechanism of acquired resistance to first-line treatment with first-and second-generation EGFR-TKI is the T790M mutation, with approximately 30 to 60 percent of patients whose disease progresses acquiring the mutation.
The 1-2 combo of drugs -- one attacking epidermal growth factor receptor, or EGFR, and another one targeting tumor necrosis factor -- prevents the cancer from using TNF to escape.
The authors have found the promising potential of this peptide as an intracellular delivery vehicle directed to EGFR-positive cells.
Between 1996 and 2008 there was a trend to initiate dialysis at progressively higher estimated GFR, eGFR.
The decline in eGFR over the years following initial TKV measurement is significantly different between all five patient subclasses, with those in subclass 1E having the most rapid decline.
Common combinations with egfr
These word pairs occur most frequently in English texts:
- or egfr 3×
- egfr mutations 2×
- egfr and 2×
- in egfr 2×